Is it possible to block-non vpn traffic on specific device (MAC address)

It will report errors on muti-wan and clients page for firmware 4.5.
Not recommended to downgrade firmware with keeping configuration.

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If you set to "VPN Policy Base on the Client Device" and for example define your Desktop to use the VPN, this Desktop won't be able to connect to the internet if the VPN service is down (like a built in Killer Switch) - you can try this by input an invalid VPN configuration and click Connect.

If you Disable/Disconnect from the VPN all clients will revert to the standard, meaning disabling a VPN client just ignore any VPN rules which is confusing as I assume you were looking at the rules as always active.