ttyUSB0 changing to ttyUSB1 and vice-versa

Hi all,
Using Ubuntu, I am connecting to dominoPi using
picocom -b 115200 /dev/ttyUSB0

but after a random amount of time it is changing to ttyUSB1 and picocom is getting disconnected.
If I connect using ttyUSB1,
picocom -b 115200 /dev/ttyUSB1
after sometime it is changing to ttyUSB0 and getting disconnected.

what can be the solution of this problem.

Could it be a bad USB cable / connection? When a FTDI chip looses power and restarts Ubuntu detects it again, so then the number goes up.