Is it possible to route all traffic to a remote server through Wireguard

The GL firmware supports that, see Build your own WireGuard Home Server with two GL.iNet Routers - GL.iNet Router Docs 4 and Block No-VPN Traffic - GL.iNet Router Docs 4

At the end you just need to add AllowedIPs = 0.0.0.0/0,::/0 inside Peer, see How to troubleshoot WireGuard

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